Relative time-intensity curve: a new method to differentiate benign and malignant lesions on breast MRI
نویسندگان
چکیده
Material and methods MR images of 100 patients with enhancing breast lesions (64 malignant, 36 benign) obtained before and repeatedly after intravenous injection of Gd-DOTA were evaluated. Signal intensity of lesions (SIlesion) and breast (SIbreast) were measured and TIC obtained. Relative signal intensity of the lesion was calculated as (SIlesion-SIbreast)/SIbreast and plotted versus time to obtain relative TIC. Four parameters were evaluated for diagnosis of carcinoma: peak enhancement (PE), initial enhancement slope (S), time-topeak (TTP), and washout ratio (WO). Comparison of parameter performance on TIC and relative TIC has been done by the Student’s T test and the Receiver-Operator Curve (ROC) analysis.
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